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Pfizer’s vaccine shipments to Canada already primarily based on 6 doses per vial

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Pfizer and BioNTech are already assuming Canada will agree their COVID-19 vaccine vials include six doses as an alternative of 5 and are utilizing that to challenge what number of vials they’ll ship Canada within the coming weeks.

A number of provinces say efforts to get that sixth dose are extraordinarily hit and miss, even with the particular syringes wanted to do it.

Learn extra:
Officials insist Canada still on track for 4M Pfizer doses by March despite planning data

Pfizer solely formally requested on Jan. 22 that Canada be part of america and Europe in altering the vaccine’s authorization to replicate that the vials contained sufficient vaccine to get six doses slightly than 5.

That will imply they may ship fewer vials of vaccine to Canada and nonetheless meet their contract to ship 4 million doses by March 31, and 40 million by the autumn.

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Deputy chief public well being officer Dr. Howard Njoo stated Thursday that Well being Canada continues to be reviewing the request to formally change the label and is inspecting whether or not that sixth dose might be extracted persistently sufficient to warrant a proper adjustment.

However Pfizer is already utilizing the six doses because it calculates how a lot vaccine Canada goes to get for all shipments after Feb. 8.


Click to play video 'Alberta health minister is furious over vaccine delivery changes'



Alberta well being minister is livid over vaccine supply adjustments


Alberta well being minister is livid over vaccine supply adjustments

A doc distributed to the provinces Thursday exhibits they are going to be getting 2,722 vials of vaccine between Feb. 8 and March 31. By Pfizer’s math, these vials include 3.2 million doses of vaccine. However utilizing Canada’s math, at 5 doses per vial, there are solely 2.7 million doses at present allotted for Canada in that timeframe, which would depart Pfizer half 1,000,000 doses shy of its contract.

“Pfizer is utilizing a unique calculation than my workforce is at present utilizing,” stated Maj.-Gen. Dany Fortin, the navy commander introduced in to handle logistics for the federal vaccine rollout.

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However Fortin stated Pfizer continues to be dedicated to 4 million doses by the tip of March, “full cease.” If Canada rejects the change, Pfizer would ship extra vials to account for it, he stated.

The differing numbers left provincial governments confused and offended Thursday. Whereas the chart they got clearly lays out that Canada and Pfizer are utilizing two completely different calculations, provincial leaders professed exasperation.

Learn extra:
Pfizer pushes Health Canada to stretch vaccine doses per vial as demand mounts

“We are able to’t vaccinate individuals after we aren’t getting vaccines and after we aren’t getting correct data from the federal authorities,” stated Saskatchewan Premier Scott Moe.

Getting a sixth dose from a vial persistently requires using a particular syringe often known as a low-dead-volume syringe, which traps much less vaccine between the stopper and the needle when a vaccine is extracted from the vial and injected.

The syringes are much less widespread than the high-dead-volume variations, however Canada did have some in inventory in some jurisdictions which have already been used to attempt to get the sixth dose when potential. Canada ordered one other 37.5 million of the particular syringes within the fall, and the primary two million are set to reach subsequent week.

The remainder will arrive in a number of shipments earlier than the center of April.

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Click to play video 'Confusion and concern over vaccine shipment delays'



Confusion and concern over vaccine cargo delays


Confusion and concern over vaccine cargo delays

Dr. Deena Hinshaw, Alberta’s chief medical officer, stated well being officers are getting the sixth dose once they can, however it could possibly’t be assured from every vial and has solely been achieved in about half the vials of Pfizer vaccine utilized in Alberta up to now.

Hinshaw stated it’s not all the time potential to get six doses for a lot of causes, together with a world scarcity of a specialised sort of syringe wanted to get the additional dose, and that even with that needle, professionals have solely been about profitable at doing it in about 75 per cent of the time.

A spokesman for Moe’s authorities stated Saskatchewan has additionally gotten a sixth dose from about half of its vials nevertheless it isn’t a given.

“As a result of this inconsistency, well being officers view the flexibility to attract further vaccine as a surplus profit, not a benchmark to plan for,” stated Moe’s communications director Jim Billington.

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Learn extra:
Canada adds 4,876 new coronavirus cases as anger builds over reduced vaccines

A spokesman for the Quebec authorities stated Thursday that vaccinators there have typically been capable of get sixth doses however solely in a minority of vials used.

Ontario Well being Minister Christine Elliott stated her province has requested staff to do what they will to get that sixth dose however didn’t point out the success fee.

“It actually, actually helps us when we’ve got the scarcity of vaccines coming in proper now from Pfizer,” she stated.

Provinces have already needed to pause elements of their vaccination campaigns as a result of Pfizer stopped sending vaccines to Canada solely this week whereas it expands its plant in Belgium. Initially, the corporate stated the manufacturing delay was going to chop Canada’s deliveries in half over 4 weeks.


Click to play video 'Feds: Canada’s COVID-19 vaccine rollout plan remains on track'



Feds: Canada’s COVID-19 vaccine rollout plan stays on monitor


Feds: Canada’s COVID-19 vaccine rollout plan stays on monitor

However the cuts had been far deeper, with fewer than 340,000 doses arriving or deliberate to reach between Jan. 18 and Feb. 14, as an alternative of just about 1.2 million. Shipments stopped solely this week, however are to renew with small batches within the subsequent two weeks earlier than greater shipments begin the week of Feb. 15.

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Pfizer was going to catch up by sending greater than beforehand anticipated within the final a part of February and all through March, however now, with the change to the doses per vial, it barely has to extend the beforehand deliberate shipments in any respect.

Fortin agreed the slowdown isn’t ultimate however he’s “cautiously optimistic” that Pfizer will stay as much as its contract.

Seven weeks after vaccinations started in Canada, greater than 800,000 individuals have had a minimum of one shot, and nearly 91,000 have acquired each of the required doses of both Pfizer-BioNTech or Moderna vaccines. Moderna’s vaccine has not had the identical extra-dose state of affairs as Pfizer.



© 2021 The Canadian Press

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